Interactor 1: ARPC3 (O15145)
Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit) (p21-ARC)
Gene: ARPC3
Interactor 2: ARP2 (P61160)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.981 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 28514442, 33961781, 35271311, 37071682, 38334954, 39358380, 26496610, 29568061, 24981860, 35235311, 31839598, 39422127 |
| Identification Methods | affinity chromatography technology, cross-linking study, proximity labelling technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Actin~P21-Arc |
| Common GO terms | GO:0003779 - actin binding GO:0005200 - structural constituent of cytoskeleton GO:0005634 - nucleus GO:0005829 - cytosol GO:0005885 - Arp2/3 protein complex and 6 others more... |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025