Interactor 1: TLR3 (O15455)
Toll-like receptor 3 (CD antigen CD283)
Gene: TLR3

Interactor 2: TRAF3 (Q13114)
TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3)
Gene: TRAF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 21903422
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002224 - toll-like receptor signaling pathway
GO:0005737 - cytoplasm
GO:0007165 - signal transduction
GO:0010008 - endosome membrane
GO:0051607 - defense response to virus
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 904
Hs

1 568
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Last updated: 15 Jul 2024