HitPredict

Interactor 1: YKT6 (O15498)
Synaptobrevin homolog YKT6 (EC 2.3.1.-)
Gene: YKT6

Interactor 2: STX12 (Q86Y82)
Syntaxin-12
Gene: STX12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNARE~Synaptobrevin
Common GO terms	GO:0000139 - Golgi membrane GO:0005484 - SNAP receptor activity GO:0005794 - Golgi apparatus GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 198 Hs			1 276
+	Dm
		1098114 Q9W3M8_DROME (1-196): 9.21e-71: 215: 61.74		STX1A_DROME (4-273): 6.4e-64: 204: 22.10
+	Mm
		139056 SC22B_MOUSE (1-196): 2.72e-63: 196: 19.60		STX1A_MOUSE (18-273): 2.43e-67: 212: 24.05
+	Hs
		263179 SC22B_HUMAN (1-196): 2.72e-63: 196: 19.60		STX2_HUMAN (16-272): 3.38e-66: 209: 26.62
+	At
		812702 VA722_ARATH (22-194): 8.26e-69: 210: 20.43		SY121_ARATH (8-252): 2.96e-59: 193: 18.75
+	At
		1352985 VA721_ARATH (22-194): 3.17e-68: 209: 21.51		SYP42_ARATH (2-273): 1.6e-59: 193: 21.79
+	At
		1378372 VA721_ARATH (22-194): 3.17e-68: 209: 21.51		SY121_ARATH (8-252): 2.96e-59: 193: 18.75
+	At
		955702 VA721_ARATH (22-194): 3.17e-68: 209: 21.51		SYP22_ARATH (1-258): 1.52e-59: 191: 24.43
+	Hs
		178309 YKT6_HUMAN (1-198): 2.95e-72: 218: 100.00		STX7_HUMAN (8-272): 1.12e-55: 181: 51.70
+	At
		249597 YKT61_ARATH (1-198): 5.24e-69: 210: 44.50		SYP41_ARATH (2-273): 4.62e-58: 189: 21.07
+	At
		249598 VA721_ARATH (22-194): 3.17e-68: 209: 21.51		SYP41_ARATH (2-273): 4.62e-58: 189: 21.07
+	At
		1352937 VA721_ARATH (22-194): 3.17e-68: 209: 21.51		SY122_ARATH (1-252): 6.92e-57: 187: 20.53
+	Hs
		180867 YKT6_HUMAN (1-198): 2.95e-72: 218: 100.00		STX3_HUMAN (5-250): 2.56e-53: 176: 25.20
+	Dm
		1178804 Q9W3M8_DROME (1-196): 9.21e-71: 215: 61.74		Q7K0X9_DROME (21-274): 3.74e-54: 178: 31.84
+	At
		1352876 VA721_ARATH (22-194): 3.17e-68: 209: 21.51		SYP43_ARATH (2-273): 2.11e-55: 183: 20.00
+	At
		812689 VA722_ARATH (22-194): 8.26e-69: 210: 20.43		SY111_ARATH (4-252): 1.64e-51: 172: 19.77
+	At
		1114744 VA721_ARATH (22-194): 3.17e-68: 209: 21.51		SY111_ARATH (4-252): 1.64e-51: 172: 19.77
+	Dm
		1374251 Q9W3M8_DROME (1-196): 9.21e-71: 215: 61.74		Q9VU45_DROME (13-269): 2.95e-49: 166: 28.41
+	Hs
		178331 SC22B_HUMAN (1-196): 2.72e-63: 196: 19.60		STX7_HUMAN (8-272): 1.12e-55: 181: 51.70
+	At
		1258650 VA721_ARATH (22-194): 3.17e-68: 209: 21.51		SY132_ARATH (107-252): 5.34e-12: 66.6: 32.88
+	Sc
		699190 YKT6_YEAST (1-198): 9.98e-69: 209: 47.00		PEP12_YEAST (30-249): 1.29e-11: 65.5: 25.64