HitPredict

Interactor 1: MAFG (O15525)
Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G) (hMAF)
Gene: MAFG

Interactor 2: NF2L1 (Q14494)
Endoplasmic reticulum membrane sensor NFE2L1 (Locus control region-factor 1) (LCR-F1) (Nuclear factor erythroid 2-related factor 1) (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Protein NRF1, p120 form) (Transcription factor 11) (TCF-11) [Cleaved into: Transcription factor NRF1 (Protein NRF1, p110 form)]
Gene: NFE2L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.882

The method score is based on:

Property Details
Experiments 8932385, 23661758, 20102225, unassigned1913
Identification Methods pull down, fluorescent resonance energy transfer, peptide array, split luciferase complementation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_Maf~bZIP_Maf
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 1 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 162
Hs

1 772
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Last updated: 15 Jul 2024