Interactor 1: CASC3 (O15234)
Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node gene 51 protein) (MLN 51) (Protein barentsz) (Btz)
Gene: CASC3

Interactor 2: IF4A1 (P60842)
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)
Gene: EIF4A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments unassigned3799
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains Btz~DEAD, Btz~Helicase_C
Common GO terms GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005829 - cytosol
GO:0010494 - cytoplasmic stress granule
GO:0048471 - perinuclear region of cytoplasm
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 703
Hs

1 406
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Sc
+ Sc
+ Hs

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Last updated: 11Aug2025