Interactor 1: STX1A (O16000)
Syntaxin-1A homolog (Uncoordinated protein 64)
Gene: unc-64

Interactor 2: UNC18 (P34815)
Acetylcholine regulator unc-18 (Uncoordinated protein 18)
Gene: unc-18

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.928

The method score is based on:

Property Details
Experiments 9442061, 14550897, 10366611, 8939465, 19032153, 22593072
Identification Methods biochemical, affinity chromatography technology, pull down
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SNARE~Sec1, Sec1~Syntaxin
Common GO terms GO:0005886 - plasma membrane
GO:0006886 - intracellular protein transport
GO:0007269 - neurotransmitter secretion
GO:0007271 - synaptic transmission, cholinergic
GO:0030424 - axon
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 291
Ce

1 591
+ Mm
+ Mm
+ Rn
+ Hs
+ Mm
+ Bt
+ Rn
+ Hs
+ Hs
+ Dm
+ Rn
+ Hs
+ Rn
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs

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Last updated: 15 Jul 2024