HitPredict

Interactor 1: STX1A (O16000)
Syntaxin-1A homolog (Uncoordinated protein 64)
Gene: unc-64

Interactor 2: GOSR2 (P41941)
Golgi SNAP receptor complex member 2 homolog memb-1
Gene: memb-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	14704431
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SNARE~V-SNARE_C
Common GO terms	GO:0000149 - SNARE binding GO:0005484 - SNAP receptor activity GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 291 Ce			1 213
+	Hs
		151576 STX1A_HUMAN (3-284): 1.99e-75: 233: 63.96		GOSR2_HUMAN (1-210): 3.09e-57: 181: 32.70
+	Dm
		1098107 STX1A_DROME (1-284): 1.56e-74: 231: 66.43		GOSR2_DROME (1-210): 1.08e-50: 165: 32.56
+	Dm
		1098112 STX1A_DROME (1-284): 1.56e-74: 231: 66.43		Q9W0N6_DROME (1-211): 3.55e-48: 159: 15.28
+	Hs
		1084006 STX1A_HUMAN (3-284): 1.99e-75: 233: 63.96		VTI1B_HUMAN (2-190): 1.56e-44: 149: 15.39
+	Hs
		151566 STX4_HUMAN (3-284): 2.06e-62: 200: 36.90		GOSR2_HUMAN (1-210): 3.09e-57: 181: 32.70
+	Hs
		699289 STX2_HUMAN (3-284): 1.58e-73: 229: 54.42		VTI1B_HUMAN (2-190): 1.56e-44: 149: 15.39
+	At
		1352079 SYP42_ARATH (35-286): 3.95e-52: 175: 18.77		VTI12_ARATH (1-210): 7.22e-58: 183: 10.55
+	At
		249589 SYP41_ARATH (35-285): 1.74e-52: 175: 18.50		VTI12_ARATH (1-210): 7.22e-58: 183: 10.55
+	At
		1352078 SYP43_ARATH (32-285): 4.01e-51: 172: 19.46		VTI12_ARATH (1-210): 7.22e-58: 183: 10.55
+	Hs
		151600 STX12_HUMAN (28-271): 6.92e-51: 170: 21.86		GOSR2_HUMAN (1-210): 3.09e-57: 181: 32.70
+	Hs
		1017838 STX4_HUMAN (3-284): 2.06e-62: 200: 36.90		VTI1B_HUMAN (2-190): 1.56e-44: 149: 15.39
+	Mm
		292714 Q8BH40_MOUSE (37-289): 2.22e-56: 184: 23.05		VTI1A_MOUSE (1-213): 1.56e-50: 164: 17.43
+	Mm
		1206468 Q8BH40_MOUSE (37-289): 2.22e-56: 184: 23.05		Q91XH6_MOUSE (2-210): 8.59e-50: 163: 15.81
+	At
		249590 SYP41_ARATH (35-285): 1.74e-52: 175: 18.50		VTI11_ARATH (1-192): 3.09e-53: 171: 12.06
+	At
		1352080 SYP43_ARATH (32-285): 4.01e-51: 172: 19.46		VTI11_ARATH (1-192): 3.09e-53: 171: 12.06
+	Mm
		250839 STX7_MOUSE (37-289): 2.52e-54: 178: 23.05		VTI1B_MOUSE (2-210): 1.07e-49: 163: 15.81
+	Hs
		152170 STX16_HUMAN (4-265): 6.46e-52: 174: 20.91		VTI1A_HUMAN (1-210): 2.16e-48: 159: 17.29
+	Hs
		1205352 STX12_HUMAN (28-271): 6.92e-51: 170: 21.86		VTI1A_HUMAN (1-210): 2.16e-48: 159: 17.29
+	Hs
		269467 STX11_HUMAN (3-272): 5.84e-51: 170: 29.43		VTI1A_HUMAN (1-210): 2.16e-48: 159: 17.29
+	Hs
		1205392 STX12_HUMAN (28-271): 6.92e-51: 170: 21.86		VTI1B_HUMAN (2-190): 1.56e-44: 149: 15.39