HitPredict

Interactor 1: P73 (O15350)
Tumor protein p73 (p53-like transcription factor) (p53-related protein)
Gene: TP73

Interactor 2: AGO2 (Q9UKV8)
Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer)
Gene: AGO2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20308539
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0009791 - post-embryonic development GO:0045944 - positive regulation of transcription by RNA polymerase II and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 859
+	Hs
		186819 P73_HUMAN (1-636): 0: 1040: 100.00		AGO1_HUMAN (17-859): 0: 1179: 83.16
+	Hs
		1432536 P63_HUMAN (1-629): 0: 877: 54.39		AGO2_HUMAN (1-859): 0: 1204: 100.00
+	Hs
		1432537 P63_HUMAN (1-629): 0: 877: 54.39		AGO1_HUMAN (17-859): 0: 1179: 83.16
+	Hs
		186789 P73_HUMAN (1-636): 0: 1040: 100.00		PIWL1_HUMAN (23-826): 0: 740: 22.33
+	Hs
		1394714 P63_HUMAN (1-629): 0: 877: 54.39		PIWL1_HUMAN (23-826): 0: 740: 22.33
+	Hs
		414820 P53_HUMAN (110-379): 7.39e-139: 412: 50.00		AGO2_HUMAN (1-859): 0: 1204: 100.00
+	Hs
		414824 P53_HUMAN (110-379): 7.39e-139: 412: 50.00		AGO1_HUMAN (17-859): 0: 1179: 83.16
+	Hs
		414412 P53_HUMAN (110-379): 7.39e-139: 412: 50.00		PIWL1_HUMAN (23-826): 0: 740: 22.33
+	Dm
		1445191 Q9N6D8_DROME (23-327): 3.31e-63: 215: 23.20		AGO2_DROME (30-818): 0: 702: 30.84