Protein: PIWL1
Piwi-like protein 1 (EC 3.1.26.-)

Gene: PIWL1, PIWIL1
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q96J94

Gene Ontology (top 5):
GO:0003727 - single-stranded RNA binding
GO:0003729 - mRNA binding
GO:0004521 - RNA endonuclease activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1394717

DICER
Endoribonuclease Dicer

1

20

Small-scale

0.766

High

1394719

TDRKH
Tudor and KH domain-containing protein

4

20

Small-scale

0.694

High

1270394

SND1
Staphylococcal nuclease domain-containing protein 1

1

20

Small-scale

0.554

High

599618

STMN1
Stathmin

1

0

Small-scale

0.549

High

1394713

TRI54
Tripartite motif-containing protein 54

1

9

High-throughput

0.541

High

843872

HD
Huntingtin

1

1

High-throughput

0.515

High

896858

DYN2
Dynamin-2

1

1

High-throughput

0.515

High

777595

PDE6B
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta

1

0

High-throughput

0.513

High

927491

ATX1
Ataxin-1

1

0

High-throughput

0.493

High

186789

P73
Tumor protein p73

1

9

High-throughput

0.479

High

302612

RNF8
E3 ubiquitin-protein ligase RNF8

1

5

Small-scale

0.479

High

414412

P53
Cellular tumor antigen p53

1

9

High-throughput

0.479

High

446013

ENOA
Alpha-enolase

1

1

High-throughput

0.479

High

461816

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

996808

TBA1B
Tubulin alpha-1B chain

1

6

Small-scale

0.479

High

1044376

HSF2
Heat shock factor protein 2

1

2

High-throughput

0.479

High

1106039

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

16

High-throughput

0.479

High

1108667

TBB3
Tubulin beta-3 chain

1

7

Small-scale

0.479

High

1144124

TEBP
Prostaglandin E synthase 3

1

9

High-throughput

0.479

High

1308575

NUDC3
NudC domain-containing protein 3

1

6

High-throughput

0.479

High

1394712

Q9BPW0
Serine/threonine-protein phosphatase

1

5

High-throughput

0.479

High

1394714

P63
Tumor protein 63

1

9

High-throughput

0.479

High

1394715

CYBP
Calcyclin-binding protein

1

1

High-throughput

0.479

High

1394718

NUDC
Nuclear migration protein nudC

1

6

High-throughput

0.479

High

208550

PJA2
E3 ubiquitin-protein ligase Praja-2

1

3

High-throughput

0.445

High

1153215

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

2

High-throughput

0.445

High

1394711

DNJC7
DnaJ homolog subfamily C member 7

1

11

High-throughput

0.445

High

1394716

CHIP
E3 ubiquitin-protein ligase CHIP

1

11

High-throughput

0.445

High

76566

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

3

High-throughput

0.437

High

1141861

EEA1
Early endosome antigen 1

1

4

High-throughput

0.437

High

1245568

Q6PK50
HSP90AB1 protein

1

20

High-throughput

0.437

High

1384524

Q96BE0
Heat shock cognate 71 kDa protein

1

8

High-throughput

0.437

High

347251

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

1360725

JPH3
Junctophilin-3

1

0

High-throughput

0.268

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025