HitPredict

Interactor 1: HDAC3 (O15379)
Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) (RPD3-2) (SMAP45)
Gene: HDAC3

Interactor 2: H2A1A (Q96QV6)
Histone H2A type 1-A (H2A-clustered histone 1) (Histone H2A/r)
Gene: H2AC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	24722339
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Hist_deacetyl~Histone
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 428 Hs			1 131
+	Hs
		1110006 HDAC1_HUMAN (3-385): 0: 588: 62.92		H2A1A_HUMAN (1-131): 9.86e-70: 207: 100.00
+	Hs
		1368066 HDAC2_HUMAN (3-422): 0: 580: 58.63		H2A1A_HUMAN (1-131): 9.86e-70: 207: 100.00
+	Hs
		1109819 HDAC1_HUMAN (3-385): 0: 588: 62.92		H2A2A_HUMAN (1-129): 7.51e-66: 197: 92.25
+	Hs
		418970 HDAC1_HUMAN (3-385): 0: 588: 62.92		H2A1B_HUMAN (1-129): 1.57e-65: 196: 91.47
+	Hs
		502345 HDAC1_HUMAN (3-385): 0: 588: 62.92		H2A1_HUMAN (1-129): 1.09e-65: 196: 92.25
+	Hs
		1162852 HDAC2_HUMAN (3-422): 0: 580: 58.63		H2A2C_HUMAN (1-129): 1.36e-65: 196: 92.25
+	Hs
		591757 HDAC2_HUMAN (3-422): 0: 580: 58.63		H2AX_HUMAN (1-131): 2.14e-64: 194: 85.93
+	At
		307559 HDA6_ARATH (3-423): 0: 520: 55.32		H2A3_ARATH (1-129): 4.78e-62: 187: 73.08
+	Sp
		148998 PHD1_SCHPO (3-407): 0: 519: 56.27		H2A2_SCHPO (1-121): 8.92e-54: 166: 81.30
+	Hs
		419252 HDAC6_HUMAN (5-320): 3.51e-103: 333: 23.24		H2A1B_HUMAN (1-129): 1.57e-65: 196: 91.47
+	Hs
		502578 HDAC6_HUMAN (5-320): 3.51e-103: 333: 23.24		H2A1_HUMAN (1-129): 1.09e-65: 196: 92.25
+	Hs
		591870 HDAC6_HUMAN (5-320): 3.51e-103: 333: 23.24		H2AX_HUMAN (1-131): 2.14e-64: 194: 85.93
+	Sc
		419481 HDA1_YEAST (4-351): 1.16e-115: 355: 21.56		H2A1_YEAST (16-129): 5.31e-53: 164: 78.95