HitPredict

Interactor 1: IPO8 (O15397)
Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8)
Gene: IPO8

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cse1~Ras, IBN_N~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1037 Hs			1 192
+	Hs
		334741 IPO7_HUMAN (1-1031): 0: 816: 64.57		RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00
+	Hs
		934052 XPO2_HUMAN (2-1000): 3.15e-167: 518: 18.25		RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00
+	Hs
		934165 XPO2_HUMAN (2-1000): 3.15e-167: 518: 18.25		RHOJ_HUMAN (2-189): 1.39e-80: 240: 60.64
+	Hs
		934040 XPO2_HUMAN (2-1000): 3.15e-167: 518: 18.25		CDC42_HUMAN (1-192): 5.32e-78: 232: 70.31
+	Hs
		934043 XPO2_HUMAN (2-1000): 3.15e-167: 518: 18.25		RHOA_HUMAN (5-192): 1.33e-75: 226: 57.98
+	Hs
		988586 TNPO1_HUMAN (12-858): 4.89e-147: 463: 13.24		RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00
+	Hs
		955728 IPO11_HUMAN (1-996): 1.25e-122: 400: 16.00		CDC42_HUMAN (1-192): 5.32e-78: 232: 70.31
+	Hs
		1015889 IPO11_HUMAN (1-996): 1.25e-122: 400: 16.00		RHOG_HUMAN (1-192): 1.18e-77: 231: 71.35
+	Hs
		955489 IPO9_HUMAN (4-994): 1.61e-121: 399: 14.71		CDC42_HUMAN (1-192): 5.32e-78: 232: 70.31
+	Hs
		1015689 IPO9_HUMAN (4-994): 1.61e-121: 399: 14.71		RHOG_HUMAN (1-192): 1.18e-77: 231: 71.35
+	Hs
		962611 IPO11_HUMAN (1-996): 1.25e-122: 400: 16.00		RHOA_HUMAN (5-192): 1.33e-75: 226: 57.98
+	Hs
		962392 IPO9_HUMAN (4-994): 1.61e-121: 399: 14.71		RHOA_HUMAN (5-192): 1.33e-75: 226: 57.98
+	Hs
		988372 IMB1_HUMAN (5-840): 3.26e-111: 367: 12.51		RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00