HitPredict

Interactor 1: GLYG2 (O15488)
Glycogenin-2 (GN-2) (GN2) (EC 2.4.1.186)
Gene: GYG2

Interactor 2: GYS1 (P13807)
Glycogen [starch] synthase, muscle (EC 2.4.1.11) (Glycogen synthase 1)
Gene: GYS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.911

Property	Details
Experiments	28514442, 33961781, 35271311, 16189514
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Glyco_transf_8~Glycogen_syn
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005978 - glycogen biosynthetic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 501 Hs			1 737
+	Hs
		568616 GLYG_HUMAN (34-359): 5.16e-142: 413: 54.41		GYS1_HUMAN (1-737): 0: 1422: 100.00
+	Hs
		192013 GLYG2_HUMAN (1-501): 0: 688: 100.00		GYS2_HUMAN (1-658): 0: 1118: 72.53
+	Ce
		115240 GYG1_CAEEL (37-500): 2.07e-174: 499: 35.98		GYS_CAEEL (25-662): 0: 1079: 54.04
+	Sc
		657182 GLG1_YEAST (35-472): 5.81e-130: 392: 22.39		GYS1_YEAST (23-660): 0: 1066: 54.49
+	Sc
		692499 GLG1_YEAST (35-472): 5.81e-130: 392: 22.39		GYS2_YEAST (23-660): 0: 1061: 53.96
+	Ce
		234306 O45819_CAEEL (36-275): 2.34e-102: 310: 50.00		GYS_CAEEL (25-662): 0: 1079: 54.04
+	Sc
		657191 GLG2_YEAST (34-362): 3.19e-96: 297: 24.60		GYS1_YEAST (23-660): 0: 1066: 54.49
+	Sc
		692513 GLG2_YEAST (34-362): 3.19e-96: 297: 24.60		GYS2_YEAST (23-660): 0: 1061: 53.96