HitPredict

Interactor 1: GYS2 (P27472)
Glycogen [starch] synthase isoform 2 (EC 2.4.1.11)
Gene: GSY2

Interactor 2: GLG1 (P36143)
Glycogenin-1 (EC 2.4.1.186) (Glycogen synthesis initiator protein 1) (Glycogenin glucosyltransferase 1)
Gene: GLG1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.893

Property	Details
Experiments	18467557, 16554755, 37968396, 28183979
Identification Methods	protein complementation assay, affinity chromatography technology, dihydrofolate reductase reconstruction, tandem affinity purification
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Glyco_transf_8~Glycogen_syn
Common GO terms	GO:0005737 - cytoplasm GO:0005978 - glycogen biosynthetic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 616
+	Sc
		657182 GYS1_YEAST (1-692): 0: 1220: 82.51		GLG1_YEAST (1-616): 0: 874: 100.00
+	Sc
		692513 GYS2_YEAST (1-691): 0: 1228: 100.00		GLG2_YEAST (1-363): 1.41e-139: 412: 43.01
+	Sc
		657191 GYS1_YEAST (1-692): 0: 1220: 82.51		GLG2_YEAST (1-363): 1.41e-139: 412: 43.01
+	Hs
		192008 GYS1_HUMAN (4-663): 0: 1078: 54.92		GLYG2_HUMAN (4-384): 1.5e-122: 373: 25.46
+	Hs
		568616 GYS1_HUMAN (4-663): 0: 1078: 54.92		GLYG_HUMAN (4-323): 2.12e-108: 331: 24.72
+	Hs
		192013 GYS2_HUMAN (13-622): 0: 1019: 53.28		GLYG2_HUMAN (4-384): 1.5e-122: 373: 25.46
+	Ce
		115240 GYS_CAEEL (6-620): 0: 1017: 52.82		GYG1_CAEEL (5-351): 1.26e-112: 345: 26.80
+	Ce
		234306 GYS_CAEEL (6-620): 0: 1017: 52.82		O45819_CAEEL (5-301): 2.21e-92: 288: 27.18