Interactor 1: KLOT (O35082)
Klotho (EC 3.2.1.31) [Cleaved into: Klotho peptide]
Gene: Kl
Interactor 2: FGFR3 (Q61851)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (Heparin-binding growth factor receptor) (CD antigen CD333)
Gene: FGFR3
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.646 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19966287 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Glyco_hydro_1~I-set |
| Common GO terms | GO:0008543 - fibroblast growth factor receptor signaling pathway GO:0017134 - fibroblast growth factor binding GO:0030501 - positive regulation of bone mineralization GO:0055074 - calcium ion homeostasis GO:0090080 - positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
