HitPredict

Interactor 1: MDM4 (O35618)
Protein Mdm4 (Double minute 4 protein) (Mdm2-like p53-binding protein) (Protein Mdmx) (p53-binding protein Mdm4)
Gene: MDM4

Interactor 2: 1433G (P61982)
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: Ywhag

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	21148311, 24190973
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 489 Mm			1 247
+	Hs
		169269 MDM4_HUMAN (1-489): 0: 654: 83.71		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		169266 MDM4_HUMAN (1-489): 0: 654: 83.71		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		169280 MDM4_HUMAN (1-489): 0: 654: 83.71		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		169244 MDM4_HUMAN (1-489): 0: 654: 83.71		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		169273 MDM4_HUMAN (1-489): 0: 654: 83.71		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		169241 MDM4_HUMAN (1-489): 0: 654: 83.71		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		169245 MDM4_HUMAN (1-489): 0: 654: 83.71		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		926930 MDM2_HUMAN (2-487): 0: 550: 30.16		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		646805 MDM2_HUMAN (2-487): 0: 550: 30.16		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Mm
		620839 MDM2_MOUSE (2-487): 0: 533: 30.43		1433T_MOUSE (2-245): 3e-105: 306: 70.73
+	Hs
		683969 MDM2_HUMAN (2-487): 0: 550: 30.16		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16