HitPredict

Interactor 1: NR1I3 (O35627)
Nuclear receptor subfamily 1 group I member 3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67)
Gene: NR1I3

Interactor 2: Q8BK32 (Q8BK32)
Nuclear receptor corepressor 1
Gene: Ncor1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	14561088
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003677 - DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 358 Mm			1 291
+	Hs
		261383 THB_HUMAN (18-357): 1.87e-111: 334: 27.86		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		261568 NR1H4_HUMAN (4-356): 5.72e-106: 321: 28.76		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		261399 RXRA_HUMAN (15-357): 6.76e-105: 317: 22.54		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		500510 THB_HUMAN (18-357): 1.87e-111: 334: 27.86		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		1069095 Q15156_HUMAN (19-356): 1.73e-105: 328: 27.27		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Mm
		740772 THB_MOUSE (18-357): 3.05e-111: 333: 27.86		Q8BK32_MOUSE (1-291): 4.73e-135: 385: 100.00
+	Hs
		795610 NR4A2_HUMAN (20-357): 4.35e-107: 327: 26.90		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		261429 HNF4A_HUMAN (2-357): 4.73e-98: 300: 21.94		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		261369 ESR1_HUMAN (1-357): 8.26e-96: 298: 22.31		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		1300897 NR1H4_HUMAN (4-356): 5.72e-106: 321: 28.76		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		261493 NR1H3_HUMAN (4-357): 6.54e-96: 294: 29.27		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		587211 RXRA_HUMAN (15-357): 6.76e-105: 317: 22.54		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		818890 RXRG_HUMAN (9-357): 3.23e-102: 310: 22.73		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Mm
		193216 NR1I3_MOUSE (1-358): 1.84e-103: 310: 100.00		NCOR2_MOUSE (1-290): 9.03e-123: 388: 52.40
+	Xl
		546248 THAA_XENLA (18-357): 4.44e-109: 326: 27.98		Q1W3Z6_XENLA (4-290): 1.92e-116: 370: 51.21
+	Xl
		546251 THAA_XENLA (18-357): 4.44e-109: 326: 27.98		NCOR1_XENLA (1-290): 2.65e-116: 369: 71.72
+	Hs
		782706 HNF4A_HUMAN (2-357): 4.73e-98: 300: 21.94		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		370824 ESR1_HUMAN (1-357): 8.26e-96: 298: 22.31		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		500380 RARB_HUMAN (19-357): 7.92e-97: 296: 26.10		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		1025275 NR1H3_HUMAN (4-357): 6.54e-96: 294: 29.27		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40