HitPredict

Interactor 1: SYNJ1 (O43426)
Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1)
Gene: SYNJ1

Interactor 2: SH3G1 (Q99961)
Endophilin-A2 (EEN fusion partner of MLL) (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1)
Gene: SH3GL1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10542231
Identification Methods	unspecified method, peptide array
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016191 - synaptic vesicle uncoating GO:0098793 - presynapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1573 Hs			1 368
+	Hs
		203249 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Rn
		193638 SYNJ1_RAT (1-1573): 0: 1317: 88.27		SH3G1_RAT (1-368): 5.26e-88: 271: 92.94
+	Mm
		88460 D3Z656_MOUSE (1-1573): 0: 1312: 88.66		SH3G3_MOUSE (1-367): 8.72e-87: 267: 63.76
+	Rn
		192354 SYNJ1_RAT (1-1573): 0: 1317: 88.27		SH3G2_RAT (1-368): 2.02e-84: 261: 68.48
+	Rn
		192356 SYNJ1_RAT (1-1573): 0: 1317: 88.27		SH3G3_RAT (1-368): 2.22e-84: 261: 62.77
+	Mm
		88459 D3Z656_MOUSE (1-1573): 0: 1312: 88.66		SH3G2_MOUSE (1-368): 8.98e-84: 260: 69.02
+	Hs
		203251 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		PACN1_HUMAN (16-363): 9.35e-37: 139: 14.89
+	Hs
		203262 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		PACN2_HUMAN (16-364): 1.92e-34: 134: 14.97
+	Hs
		203246 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		SH3Y1_HUMAN (230-362): 4.51e-28: 114: 32.41
+	Hs
		203250 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		SRBS1_HUMAN (235-363): 3.59e-15: 79.2: 25.95
+	Hs
		203192 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		SRBS2_HUMAN (270-363): 9.46e-12: 68.6: 23.96
+	Hs
		203218 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Rn
		192744 SYNJ1_RAT (1-1573): 0: 1317: 88.27		SRBS2_RAT (264-363): 2.11e-12: 70.5: 22.55
+	Dm
		1137151 Q5U0V7_DROME (1-1130): 0: 1048: 48.47		SH3G3_DROME (1-367): 1.34e-75: 239: 48.10
+	Hs
		166042 SYNJ2_HUMAN (1-1418): 0: 1118: 41.56		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Ce
		70018 SYNJ_CAEEL (5-1160): 0: 938: 39.64		SH3GH_CAEEL (1-366): 1.14e-70: 227: 44.76
+	Dm
		112574 Q5U0V7_DROME (1-1130): 0: 1048: 48.47		M9ND00_DROME (235-364): 4.29e-12: 69.6: 16.91
+	Dm
		993185 Q5U0V7_DROME (1-1130): 0: 1048: 48.47		GRAP_DROME (301-360): 1.2e-10: 62.4: 48.33
+	Mm
		956956 SHIP1_MOUSE (505-1251): 6.64e-154: 502: 20.90		PPIP1_MOUSE (13-363): 3.71e-32: 126: 15.92
+	Mm
		1141165 SHIP1_MOUSE (505-1251): 6.64e-154: 502: 20.90		GRB2_MOUSE (311-367): 1.59e-11: 65.2: 41.38