HitPredict

Interactor 1: TGON2 (O43493)
Trans-Golgi network integral membrane protein 2 (Trans-Golgi network glycoprotein 46) (TGN38 homolog) (hTGN46) (Trans-Golgi network glycoprotein 48) (hTGN48) (Trans-Golgi network glycoprotein 51) (hTGN51) (Trans-Golgi network protein 2)
Gene: TGOLN2

Interactor 2: ERBB2 (P04626)
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)
Gene: ERBB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35696571
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 1255
+	Hs
		383851 TENS2_HUMAN (9-345): 1.68e-22: 102: 14.33		ERBB2_HUMAN (1-1255): 0: 1282: 100.00
+	Hs
		383583 MUC1_HUMAN (17-398): 8.52e-13: 72.6: 9.42		ERBB2_HUMAN (1-1255): 0: 1282: 100.00
+	Hs
		383566 NFH_HUMAN (76-385): 7.1e-12: 69.5: 13.78		ERBB2_HUMAN (1-1255): 0: 1282: 100.00
+	Hs
		204894 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		EGFR_HUMAN (16-1253): 0: 1070: 48.40
+	Hs
		270571 MYCB2_HUMAN (16-437): 3.13e-46: 173: 14.64		ERBB3_HUMAN (5-1254): 0: 1041: 38.55
+	Hs
		1070974 TENS2_HUMAN (9-345): 1.68e-22: 102: 14.33		ERBB4_HUMAN (6-1237): 0: 1098: 45.45
+	Hs
		338550 TENS2_HUMAN (9-345): 1.68e-22: 102: 14.33		EGFR_HUMAN (16-1253): 0: 1070: 48.40
+	Hs
		554307 MUC1_HUMAN (17-398): 8.52e-13: 72.6: 9.42		ERBB4_HUMAN (6-1237): 0: 1098: 45.45
+	Hs
		601934 TENS2_HUMAN (9-345): 1.68e-22: 102: 14.33		ERBB3_HUMAN (5-1254): 0: 1041: 38.55
+	Hs
		337875 MUC1_HUMAN (17-398): 8.52e-13: 72.6: 9.42		EGFR_HUMAN (16-1253): 0: 1070: 48.40
+	Hs
		338769 TITIN_HUMAN (18-351): 1.31e-09: 62.9: 10.41		EGFR_HUMAN (16-1253): 0: 1070: 48.40
+	Hs
		554266 MUC1_HUMAN (17-398): 8.52e-13: 72.6: 9.42		ERBB3_HUMAN (5-1254): 0: 1041: 38.55
+	Hs
		205079 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		EPHB2_HUMAN (650-1103): 2.29e-122: 406: 29.47
+	Hs
		205216 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		EPHA4_HUMAN (668-1030): 3.69e-121: 401: 31.45
+	Hs
		205078 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		EPHA2_HUMAN (671-1023): 4.87e-117: 390: 33.06
+	Hs
		270580 MYCB2_HUMAN (16-437): 3.13e-46: 173: 14.64		EPHB2_HUMAN (650-1103): 2.29e-122: 406: 29.47
+	Hs
		205215 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		EPHB4_HUMAN (707-1000): 4.94e-53: 204: 38.21
+	Hs
		204943 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		IGF1R_HUMAN (337-633): 4.59e-20: 99.1: 22.92
+	Rn
		88680 D3ZQ77_RAT (244-435): 2.21e-28: 114: 19.70		INSR_RAT (357-634): 2.53e-16: 87.2: 19.87