Interactor 1: AFAD (O35889)
Afadin (Afadin adherens junction formation factor) (Protein Af-6)
Gene: Afdn

Interactor 2: PRKN (Q9JK66)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase)
Gene: PRKN

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 23393160
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0010628 - positive regulation of gene expression
GO:0030424 - axon
GO:0098978 - glutamatergic synapse
and 1 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1829
Rn

1 465
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025