HitPredict

Interactor 1: PRP4 (O43172)
U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4)
Gene: PRPF4

Interactor 2: TCPD (P50991)
T-complex protein 1 subunit delta (TCP-1-delta) (EC 3.6.1.-) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding)
Gene: CCT4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 522 Hs			1 539
+	Hs
		899553 TBL1Y_HUMAN (69-436): 1.04e-68: 231: 15.25		TCPD_HUMAN (1-539): 0: 601: 100.00
+	Hs
		882075 FBXW7_HUMAN (161-515): 2.14e-80: 266: 21.21		TCPG_HUMAN (12-537): 0: 552: 33.40
+	Hs
		899326 WDR5_HUMAN (6-350): 7.89e-64: 212: 15.52		TCPD_HUMAN (1-539): 0: 601: 100.00
+	Hs
		882119 TBL1Y_HUMAN (69-436): 1.04e-68: 231: 15.25		TCPG_HUMAN (12-537): 0: 552: 33.40
+	Hs
		1407533 TBL1Y_HUMAN (69-436): 1.04e-68: 231: 15.25		TCPH_HUMAN (12-538): 0: 548: 32.34
+	Hs
		876146 TBL1Y_HUMAN (69-436): 1.04e-68: 231: 15.25		TCPE_HUMAN (13-535): 0: 539: 37.88
+	Hs
		881861 WDR5_HUMAN (6-350): 7.89e-64: 212: 15.52		TCPG_HUMAN (12-537): 0: 552: 33.40
+	Hs
		965190 WDR5_HUMAN (6-350): 7.89e-64: 212: 15.52		TCPH_HUMAN (12-538): 0: 548: 32.34
+	Hs
		875898 WDR5_HUMAN (6-350): 7.89e-64: 212: 15.52		TCPE_HUMAN (13-535): 0: 539: 37.88
+	Hs
		899492 POC1B_HUMAN (38-261): 8.58e-35: 138: 8.93		TCPD_HUMAN (1-539): 0: 601: 100.00
+	Hs
		899463 WDR5B_HUMAN (38-258): 1.56e-27: 114: 8.41		TCPD_HUMAN (1-539): 0: 601: 100.00
+	Hs
		882051 POC1B_HUMAN (38-261): 8.58e-35: 138: 8.93		TCPG_HUMAN (12-537): 0: 552: 33.40
+	Hs
		845257 LIS1_HUMAN (403-522): 4.52e-33: 131: 29.17		TCPG_HUMAN (12-537): 0: 552: 33.40
+	Hs
		876081 POC1B_HUMAN (38-261): 8.58e-35: 138: 8.93		TCPE_HUMAN (13-535): 0: 539: 37.88
+	Hs
		209218 PRP4_HUMAN (393-522): 2.58e-26: 114: 25.55		TCPG_HUMAN (12-537): 0: 552: 33.40
+	Hs
		882014 WDR5B_HUMAN (38-258): 1.56e-27: 114: 8.41		TCPG_HUMAN (12-537): 0: 552: 33.40
+	Hs
		1291941 WDR5B_HUMAN (38-258): 1.56e-27: 114: 8.41		TCPH_HUMAN (12-538): 0: 548: 32.34
+	Hs
		209325 PRP4_HUMAN (393-522): 2.58e-26: 114: 25.55		TCPH_HUMAN (12-538): 0: 548: 32.34
+	Hs
		209216 PRP4_HUMAN (393-522): 2.58e-26: 114: 25.55		TCPE_HUMAN (13-535): 0: 539: 37.88
+	Hs
		876070 POC1A_HUMAN (14-221): 4.13e-23: 103: 8.65		TCPE_HUMAN (13-535): 0: 539: 37.88