HitPredict

Interactor 1: PRP4 (O43172)
U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4)
Gene: PRPF4

Interactor 2: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (EC 3.6.1.-) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 522 Hs			1 535
+	Hs
		1007186 FBXW7_HUMAN (161-515): 2.14e-80: 266: 21.21		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		882075 FBXW7_HUMAN (161-515): 2.14e-80: 266: 21.21		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		1407533 TBL1Y_HUMAN (69-436): 1.04e-68: 231: 15.25		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		1007231 TBL1Y_HUMAN (69-436): 1.04e-68: 231: 15.25		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		610813 FBXW7_HUMAN (161-515): 2.14e-80: 266: 21.21		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		965190 WDR5_HUMAN (6-350): 7.89e-64: 212: 15.52		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		964840 WDR5_HUMAN (6-350): 7.89e-64: 212: 15.52		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		882119 TBL1Y_HUMAN (69-436): 1.04e-68: 231: 15.25		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		881861 WDR5_HUMAN (6-350): 7.89e-64: 212: 15.52		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		610855 TBL1Y_HUMAN (69-436): 1.04e-68: 231: 15.25		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		876146 TBL1Y_HUMAN (69-436): 1.04e-68: 231: 15.25		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		610601 WDR5_HUMAN (6-350): 7.89e-64: 212: 15.52		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		875898 WDR5_HUMAN (6-350): 7.89e-64: 212: 15.52		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		1007162 POC1B_HUMAN (38-261): 8.58e-35: 138: 8.93		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		882051 POC1B_HUMAN (38-261): 8.58e-35: 138: 8.93		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		845257 LIS1_HUMAN (403-522): 4.52e-33: 131: 29.17		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		610789 POC1B_HUMAN (38-261): 8.58e-35: 138: 8.93		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		876081 POC1B_HUMAN (38-261): 8.58e-35: 138: 8.93		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		882014 WDR5B_HUMAN (38-258): 1.56e-27: 114: 8.41		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		610750 WDR5B_HUMAN (38-258): 1.56e-27: 114: 8.41		TCPA_HUMAN (5-533): 0: 541: 34.30