HitPredict

Interactor 1: BUB3 (O43684)
Mitotic checkpoint protein BUB3
Gene: BUB3

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 328 Hs			1 758
+	Hs
		653959 RAE1L_HUMAN (3-326): 2.75e-99: 299: 33.63		MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56
+	Hs
		496503 LIS1_HUMAN (168-319): 3.74e-31: 122: 14.47		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Dm
		113998 Q9W1T0_DROME (2-315): 6.17e-99: 296: 26.32		M9PB30_DROME (69-755): 2.38e-24: 112: 8.39
+	Hs
		152559 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55
+	Hs
		211213 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91
+	Hs
		654026 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56
+	Hs
		152678 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55
+	Hs
		1281391 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		PRR36_HUMAN (1-607): 1.27e-15: 83.6: 10.11
+	Hs
		653951 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56
+	Hs
		1056932 SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		152622 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55
+	Hs
		152663 WDR5B_HUMAN (208-320): 1.06e-19: 89.7: 16.81		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55
+	Dm
		1370295 POC1_DROME (221-305): 7.29e-16: 79.3: 18.82		Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96
+	Mm
		903669 WDR5_MOUSE (209-320): 6.93e-20: 90.4: 16.07		KMT2C_MOUSE (228-587): 6.06e-09: 61.9: 16.84
+	Hs
		903374 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91