HitPredict

Interactor 1: BUB3 (O43684)
Mitotic checkpoint protein BUB3
Gene: BUB3

Interactor 2: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31911655
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 328 Hs			1 759
+	Hs
		211178 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1043114 POC1B_HUMAN (134-327): 7.29e-41: 150: 13.93		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		943828 RAE1L_HUMAN (3-326): 2.75e-99: 299: 33.63		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		211176 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1043499 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		792982 LIS1_HUMAN (168-319): 3.74e-31: 122: 14.47		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043469 POC1B_HUMAN (134-327): 7.29e-41: 150: 13.93		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		154680 GNB5_HUMAN (13-206): 2.53e-26: 109: 22.06		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043157 SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		903208 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		943827 RAE1L_HUMAN (3-326): 2.75e-99: 299: 33.63		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		1043509 SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		211175 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		CUL2_HUMAN (51-759): 0: 710: 27.00
+	Hs
		1042655 NLE1_HUMAN (86-326): 2.9e-49: 172: 13.10		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1042101 POC1B_HUMAN (134-327): 7.29e-41: 150: 13.93		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1041647 TAF5_HUMAN (65-295): 2.05e-24: 105: 18.35		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Mm
		1257398 FBXW7_MOUSE (1-202): 1.89e-47: 171: 20.85		CUL1_MOUSE (59-759): 0: 745: 30.55
+	Hs
		1041133 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		903207 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		903206 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		CUL1_HUMAN (59-759): 0: 745: 30.55