HitPredict

Interactor 1: CYH3 (O43739)
Cytohesin-3 (ARF nucleotide-binding site opener 3) (Protein ARNO3) (General receptor of phosphoinositides 1) (Grp1) (PH, SEC7 and coiled-coil domain-containing protein 3)
Gene: CYTH3

Interactor 2: INAVA (Q3KP66)
Innate immunity activator protein
Gene: INAVA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.719

Property	Details
Experiments	28514442, 29420262, 30355448, 33961781, 31022698
Identification Methods	affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 400 Hs			1 663
+	Hs
		1074102 CYH1_HUMAN (1-400): 4.59e-176: 498: 84.25		INAVA_HUMAN (1-663): 0: 1010: 100.00
+	Hs
		1108765 CYH2_HUMAN (3-400): 2.9e-174: 493: 80.91		INAVA_HUMAN (1-663): 0: 1010: 100.00
+	Hs
		1108772 CYH4_HUMAN (13-400): 1.81e-167: 476: 72.94		INAVA_HUMAN (1-663): 0: 1010: 100.00
+	Hs
		1074121 CYH1_HUMAN (1-400): 4.59e-176: 498: 84.25		FRM4B_HUMAN (85-373): 1.08e-106: 348: 31.89
+	Mm
		140107 CYH3_MOUSE (1-400): 1.01e-170: 484: 98.75		FRM4B_MOUSE (85-373): 3.83e-104: 341: 29.47
+	Hs
		1074119 CYH1_HUMAN (1-400): 4.59e-176: 498: 84.25		FRM4A_HUMAN (112-397): 2.82e-92: 309: 43.05
+	Hs
		1350519 CYH4_HUMAN (13-400): 1.81e-167: 476: 72.94		FRM4A_HUMAN (112-397): 2.82e-92: 309: 43.05
+	Hs
		1074111 CYH1_HUMAN (1-400): 4.59e-176: 498: 84.25		CC120_HUMAN (110-369): 7.2e-52: 191: 26.10
+	Hs
		1293344 CYH2_HUMAN (3-400): 2.9e-174: 493: 80.91		CC120_HUMAN (110-369): 7.2e-52: 191: 26.10
+	Hs
		212320 CYH3_HUMAN (12-400): 6.36e-172: 487: 100.00		CC120_HUMAN (110-369): 7.2e-52: 191: 26.10
+	Hs
		1293374 CYH4_HUMAN (13-400): 1.81e-167: 476: 72.94		CC120_HUMAN (110-369): 7.2e-52: 191: 26.10