HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: SP16H (Q9Y5B9)
FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16)
Gene: SUPT16H

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	24457600, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031491 - nucleosome binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 441 Hs			1 1047
+	Mm
		1265304 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		SP16H_MOUSE (1-1047): 0: 1332: 98.66
+	Hs
		1253312 POC1B_HUMAN (186-440): 4.25e-48: 173: 15.56		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1281516 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1288411 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1346973 NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		903647 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1356386 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Mm
		1158223 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		XPP1_MOUSE (63-437): 7.87e-70: 247: 14.43