HitPredict

Interactor 1: STX6 (O43752)
Syntaxin-6
Gene: STX6

Interactor 2: NSF (P46459)
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)
Gene: NSF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	34079125, 33961781, 35271311, 20562859
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000149 - SNARE binding GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 744
+	Hs
		235153 STX10_HUMAN (1-239): 5.84e-67: 209: 61.09		NSF_HUMAN (1-744): 0: 572: 100.00
+	Hs
		803999 STX8_HUMAN (3-236): 1.15e-36: 131: 17.45		NSF_HUMAN (1-744): 0: 572: 100.00
+	Hs
		169401 BET1_HUMAN (138-255): 1.8e-33: 119: 16.95		NSF_HUMAN (1-744): 0: 572: 100.00
+	Hs
		803988 BET1L_HUMAN (155-253): 9.93e-19: 80.7: 19.00		NSF_HUMAN (1-744): 0: 572: 100.00
+	Dm
		870085 Q9VV76_DROME (32-241): 4.95e-26: 103: 14.29		NSF2_DROME (5-742): 6.55e-166: 498: 63.21
+	Dm
		870086 Q9VVX6_DROME (142-255): 8.05e-22: 89.2: 21.93		NSF2_DROME (5-742): 6.55e-166: 498: 63.21
+	Zm
		86554 C4J0R0_MAIZE (130-253): 6.11e-27: 102: 20.16		K7VQA7_MAIZE (13-483): 1.02e-72: 254: 23.44