HitPredict

Interactor 1: SKAP2 (O75563)
Src kinase-associated phosphoprotein 2 (Pyk2/RAFTK-associated protein) (Retinoic acid-induced protein 70) (SKAP55 homolog) (SKAP-55HOM) (SKAP-HOM) (Src family-associated phosphoprotein 2) (Src kinase-associated phosphoprotein 55-related protein) (Src-associated adapter protein with PH and SH3 domains)
Gene: SKAP2

Interactor 2: RGS3 (P49796)
Regulator of G-protein signaling 3 (RGP3) (RGS3)
Gene: RGS3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 359 Hs			1 1198
+	Mm
		1113014 SKAP2_MOUSE (1-359): 1.56e-121: 356: 90.53		RGS1_MOUSE (994-1195): 1.24e-61: 211: 38.61
+	Hs
		1263850 CNKR2_HUMAN (87-295): 1.45e-45: 168: 20.00		SMUF2_HUMAN (151-666): 3.45e-77: 272: 18.48
+	Mm
		930572 CNKR2_MOUSE (87-295): 3.83e-45: 167: 19.52		KPCG_MOUSE (81-272): 5.35e-62: 227: 31.61
+	Hs
		986397 BTK_HUMAN (122-358): 7.1e-28: 116: 12.69		SMUF1_HUMAN (151-667): 1.41e-77: 274: 17.83
+	Hs
		566481 PKHA4_HUMAN (83-293): 2.34e-28: 118: 15.28		KPCA_HUMAN (124-271): 6.07e-71: 253: 30.87
+	Hs
		408682 PKHA4_HUMAN (83-293): 2.34e-28: 118: 15.28		KPCB_HUMAN (124-271): 2.1e-67: 242: 30.87
+	Hs
		408609 BTK_HUMAN (122-358): 7.1e-28: 116: 12.69		KPCB_HUMAN (124-271): 2.1e-67: 242: 30.87
+	Mm
		802302 CNKR2_MOUSE (87-295): 3.83e-45: 167: 19.52		SYT1_MOUSE (16-263): 3.3e-38: 150: 18.39