HitPredict

Interactor 1: SGTA (O43765)
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Vpu-binding protein) (UBP)
Gene: SGTA

Interactor 2: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.651

Property	Details
Experiments	12482202, 24753260, 16777091
Identification Methods	far western blotting, pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 313 Hs			1 840
+	Hs
		213427 SGTA_HUMAN (1-313): 1.79e-68: 217: 100.00		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		714151 TTC3_HUMAN (88-310): 3.46e-40: 151: 21.18		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		714148 PPP5_HUMAN (66-233): 3.75e-40: 148: 28.57		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		714464 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		320929 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		HS74L_HUMAN (1-840): 0: 959: 63.21
+	At
		99225 OE64M_ARATH (58-206): 1.1e-40: 151: 35.57		HS701_ARATH (2-604): 0: 815: 32.57
+	At
		612321 OE64C_ARATH (45-204): 1.8e-39: 147: 30.00		HS701_ARATH (2-604): 0: 815: 32.57
+	Sc
		695762 SGT2_YEAST (2-298): 1.34e-38: 141: 26.44		HSP7F_YEAST (5-697): 5.7e-137: 424: 37.61
+	Hs
		213468 SGTA_HUMAN (1-313): 1.79e-68: 217: 100.00		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Mm
		926144 SGTA_MOUSE (1-313): 3.49e-64: 206: 87.62		HSP7C_MOUSE (564-692): 1.76e-19: 95.5: 16.15
+	Hs
		564151 SGTB_HUMAN (1-311): 5.27e-54: 180: 57.24		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Mm
		926131 PPP5_MOUSE (66-233): 8.06e-41: 150: 28.57		HSP7C_MOUSE (564-692): 1.76e-19: 95.5: 16.15
+	Hs
		503738 PPP5_HUMAN (66-233): 3.75e-40: 148: 28.57		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		504954 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		483811 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		HS71B_HUMAN (571-686): 1.59e-19: 95.5: 23.93
+	Hs
		714095 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48
+	Mm
		926173 CHIP_MOUSE (66-229): 2.17e-40: 144: 26.04		HSP7C_MOUSE (564-692): 1.76e-19: 95.5: 16.15
+	Hs
		564043 PPP5_HUMAN (66-233): 3.75e-40: 148: 28.57		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		564209 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Mm
		571871 CHIP_MOUSE (66-229): 2.17e-40: 144: 26.04		HS71B_MOUSE (571-686): 9.97e-18: 89.7: 23.08