Interactor 1: SGTA (O43765)
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Vpu-binding protein) (UBP)
Gene: SGTA

Interactor 2: BAG6 (P46379)
Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)
Gene: BAG6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 25415308, 27193484, 35543156, 23246001, 23533635, 25416956, 24424410, 32296183, 16777091, 25036637, unassigned1304, 14667819, 31515488
Identification Methods pull down, affinity chromatography technology, two hybrid, x-ray crystallography, proximity labelling technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SGTA_dimer~ubiquitin
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006620 - post-translational protein targeting to endoplasmic reticulum membrane
GO:0016020 - membrane
and 4 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 313
Hs

1 1132
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Last updated: 15 Jul 2024