Interactor 1: M3K7 (O43318)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: MAP3K7
Interactor 2: BIRC1 (Q13075)
Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein)
Gene: NAIP
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.724 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11865055 |
| Identification Methods | affinity chromatography technology, pull down |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BIR~PK_Tyr_Ser-Thr |
| Common GO terms | GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0042742 - defense response to bacterium GO:0120283 - protein serine/threonine kinase binding |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025