HitPredict

Interactor 1: MYO1B (O43795)
Unconventional myosin-Ib (MYH-1c) (Myosin I alpha) (MMI-alpha) (MMIa)
Gene: MYO1B

Interactor 2: AVIL (O75366)
Advillin (p92)
Gene: AVIL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding GO:0005737 - cytoplasm GO:0005884 - actin filament GO:0007015 - actin filament organization GO:0015629 - actin cytoskeleton and 1 others more... GO:0051015 - actin filament binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1136 Hs			1 819
+	Hs
		260679 MYO5A_HUMAN (2-1125): 0: 1013: 28.64		AVIL_HUMAN (1-819): 0: 1120: 100.00
+	Hs
		117884 MYO1F_HUMAN (16-716): 0: 617: 45.78		AVIL_HUMAN (1-819): 0: 1120: 100.00
+	Hs
		69507 MYO1G_HUMAN (16-755): 0: 662: 46.50		SVIL_HUMAN (500-806): 8.27e-25: 113: 20.17
+	Hs
		117682 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		FLII_HUMAN (340-790): 1.52e-70: 255: 23.16
+	Hs
		413844 MYH9_HUMAN (694-1133): 5.37e-12: 72.7: 7.63		GELS_HUMAN (379-779): 1.56e-112: 362: 25.59
+	Hs
		117540 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		SVIL_HUMAN (500-806): 8.27e-25: 113: 20.17
+	Hs
		724803 MYH9_HUMAN (694-1133): 5.37e-12: 72.7: 7.63		FLII_HUMAN (340-790): 1.52e-70: 255: 23.16
+	Hs
		313764 MYH9_HUMAN (694-1133): 5.37e-12: 72.7: 7.63		SVIL_HUMAN (500-806): 8.27e-25: 113: 20.17
+	Hs
		313766 MYH11_HUMAN (701-1112): 2.54e-09: 63.9: 8.28		SVIL_HUMAN (500-806): 8.27e-25: 113: 20.17