HitPredict

Interactor 1: RIPK1 (Q13546)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1

Interactor 2: OTUD1 (Q5VV17)
OTU domain-containing protein 1 (EC 3.4.19.12) (DUBA-7)
Gene: OTUD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.50	0.575

Property	Details
Experiments	34876703, 23827681
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 671 Hs			1 481
+	Hs
		213963 M3K7_HUMAN (4-611): 1.97e-124: 383: 19.18		CRBG2_HUMAN (13-316): 4.23e-10: 64.3: 12.87
+	Hs
		214440 RIPK2_HUMAN (60-306): 4.49e-30: 127: 32.96		OTUD1_HUMAN (1-481): 7.82e-100: 310: 100.00
+	Mm
		946720 RIPK2_MOUSE (55-369): 5.17e-32: 132: 29.57		OTUD1_MOUSE (1-481): 2.44e-76: 248: 71.43
+	Mm
		97707 RIPK2_MOUSE (55-369): 5.17e-32: 132: 29.57		E9PWH2_MOUSE (26-254): 1.65e-10: 65.9: 10.39
+	Mm
		97708 Q547H1_MOUSE (55-369): 5.17e-32: 132: 29.57		E9PWH2_MOUSE (26-254): 1.65e-10: 65.9: 10.39
+	Hs
		319045 LYN_HUMAN (23-289): 6.19e-28: 120: 32.13		K0754_HUMAN (2-199): 8.66e-11: 66.7: 14.75
+	Hs
		215893 LCK_HUMAN (23-289): 1.31e-27: 119: 31.87		SYNJ1_HUMAN (1-278): 1.57e-09: 62.8: 13.19