Protein: OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (O-sialoglycoprotein endopeptidase) (hOSGEP) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP) (tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP)

Gene: OSGEP
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q9NPF4

Gene Ontology (top 5):
GO:0000408 - EKC/KEOPS complex
GO:0002949 - tRNA threonylcarbamoyladenosine modification
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1056536

LAGE3
EKC/KEOPS complex subunit LAGE3

7

2

Small-scale

0.964

High

1301677

PRPK
EKC/KEOPS complex subunit TP53RK

7

1

Small-scale

0.751

High

1342735

TPRKB
EKC/KEOPS complex subunit TPRKB

4

1

Small-scale

0.694

High

1315795

GON7
EKC/KEOPS complex subunit GON7

5

0

Small-scale

0.682

High

1313035

CC28B
Coiled-coil domain-containing protein 28B

3

0

High-throughput

0.646

High

275664

POP7
Ribonuclease P protein subunit p20

3

0

High-throughput

0.638

High

1244514

NUP43
Nucleoporin Nup43

3

0

High-throughput

0.638

High

1342726

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

5

Small-scale

0.618

High

1342727

MBIP1
MAP3K12-binding inhibitory protein 1

2

0

High-throughput

0.602

High

943761

PRAME
Melanoma antigen preferentially expressed in tumors

2

0

Small-scale

0.585

High

1291587

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.547

High

60424

POTEF
POTE ankyrin domain family member F

1

2

High-throughput

0.536

High

735017

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

2

High-throughput

0.536

High

972256

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

2

High-throughput

0.536

High

1237886

ENAH
Protein enabled homolog

1

1

High-throughput

0.536

High

1326929

NAA50
N-alpha-acetyltransferase 50

1

1

High-throughput

0.536

High

681612

DNJA1
DnaJ homolog subfamily A member 1

1

2

High-throughput

0.515

High

161460

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

0

High-throughput

0.513

High

273486

PPM1B
Protein phosphatase 1B

1

0

High-throughput

0.513

High

529759

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

822513

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.513

High

856194

SPSY
Spermine synthase

1

0

High-throughput

0.513

High

896685

RAB14
Ras-related protein Rab-14

1

0

High-throughput

0.513

High

900940

RHOA
Transforming protein RhoA

1

0

High-throughput

0.513

High

919675

RAP1A
Ras-related protein Rap-1A

1

0

High-throughput

0.513

High

959696

VIGLN
Vigilin

1

0

High-throughput

0.513

High

961570

FKBP3
Peptidyl-prolyl cis-trans isomerase FKBP3

1

0

High-throughput

0.513

High

1038064

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

High-throughput

0.513

High

1047815

CKAP5
Cytoskeleton-associated protein 5

1

0

High-throughput

0.513

High

1050940

DPYL3
Dihydropyrimidinase-related protein 3

1

0

High-throughput

0.513

High

1078492

TOM34
Mitochondrial import receptor subunit TOM34

1

0

High-throughput

0.513

High

1102957

QRIC1
Transcriptional regulator QRICH1

1

0

High-throughput

0.513

High

1109575

TKFC
Triokinase/FMN cyclase

1

0

High-throughput

0.513

High

1190723

HDGR2
Hepatoma-derived growth factor-related protein 2

1

0

High-throughput

0.513

High

1218463

WDFY1
WD repeat and FYVE domain-containing protein 1

1

0

High-throughput

0.513

High

1253774

PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

1

0

High-throughput

0.513

High

1267710

NDRG1
Protein NDRG1

1

0

High-throughput

0.513

High

1296021

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

1

0

High-throughput

0.513

High

1307514

VRK1
Serine/threonine-protein kinase VRK1

1

0

High-throughput

0.513

High

1315602

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.513

High

1318825

FTO
Alpha-ketoglutarate-dependent dioxygenase FTO

1

0

High-throughput

0.513

High

1331784

EHD1
EH domain-containing protein 1

1

0

High-throughput

0.513

High

1342730

ST32B
Serine/threonine-protein kinase 32B

1

0

High-throughput

0.513

High

1342731

CYH4
Cytohesin-4

1

0

High-throughput

0.513

High

1342732

DBNL
Drebrin-like protein

1

0

High-throughput

0.513

High

1342734

RRP44
Exosome complex exonuclease RRP44

1

0

High-throughput

0.513

High

1342737

STK24
Serine/threonine-protein kinase 24

1

0

High-throughput

0.513

High

177543

NVL
Nuclear valosin-containing protein-like

1

1

High-throughput

0.508

High

1191584

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.508

High

1335092

SP110
Sp110 nuclear body protein

1

1

High-throughput

0.508

High

324630

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.493

High

321839

WIZ
Protein Wiz

1

0

High-throughput

0.486

High

377708

GCR
Glucocorticoid receptor

1

0

High-throughput

0.486

High

666180

SHC1
SHC-transforming protein 1

1

0

High-throughput

0.486

High

1073159

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.486

High

1130099

RBM48
RNA-binding protein 48

1

0

High-throughput

0.486

High

1138321

MYOME
Myomegalin

1

0

High-throughput

0.486

High

1151420

CPIN1
Anamorsin

1

0

High-throughput

0.486

High

1166725

WDR82
WD repeat-containing protein 82

1

0

High-throughput

0.486

High

1206142

HPS6
BLOC-2 complex member HPS6

1

0

High-throughput

0.486

High

1239097

ZN579
Zinc finger protein 579

1

0

High-throughput

0.486

High

1285953

ZN775
Zinc finger protein 775

1

0

High-throughput

0.486

High

1286113

LENG1
Leukocyte receptor cluster member 1

1

0

High-throughput

0.486

High

1304578

PKP4
Plakophilin-4

1

0

High-throughput

0.486

High

1335474

TENS1
Tensin-1

1

0

High-throughput

0.486

High

875341

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

880594

LEG4
Galectin-4

1

0

High-throughput

0.460

High

553789

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

652326

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

713875

RYK
Tyrosine-protein kinase RYK

1

0

Small-scale

0.458

High

721519

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

909169

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1029907

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1041474

CUL2
Cullin-2

1

0

Small-scale

0.458

High

1072314

ELOC
Elongin-C

1

0

Small-scale

0.458

High

1072461

ELOB
Elongin-B

1

0

Small-scale

0.458

High

1171830

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1201917

TAXB1
Tax1-binding protein 1

1

0

High-throughput

0.458

High

1241425

MTMRE
Myotubularin-related protein 14

1

0

High-throughput

0.458

High

1298859

NP1L5
Nucleosome assembly protein 1-like 5

1

0

High-throughput

0.458

High

1327113

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

1327700

SHRPN
Sharpin

1

0

Small-scale

0.458

High

1331363

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1335496

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

1342509

DLRB1
Dynein light chain roadblock-type 1

1

0

High-throughput

0.458

High

1342729

MTMRA
Myotubularin-related protein 10

1

0

High-throughput

0.458

High

1033084

ZN211
Zinc finger protein 211

1

0

High-throughput

0.426

High

1288194

CMBL
Carboxymethylenebutenolidase homolog

1

0

High-throughput

0.426

High

58381

HYKK
Hydroxylysine kinase

3

0

High-throughput

0.347

High

158303

LIN7A
Protein lin-7 homolog A

1

0

High-throughput

0.279

Low

307454

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.279

Low

421352

HYEP
Epoxide hydrolase 1

1

0

High-throughput

0.279

Low

1045064

CD166
CD166 antigen

1

0

High-throughput

0.279

Low

1103899

ANO4
Anoctamin-4

1

0

High-throughput

0.279

Low

1342728

CYRIB
CYFIP-related Rac1 interactor B

1

0

High-throughput

0.279

Low

1342736

JAM1
Junctional adhesion molecule A

1

0

High-throughput

0.279

Low

844757

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.269

Low

857932

CRIP2
Cysteine-rich protein 2

1

0

High-throughput

0.265

Low

1290016

REX1B
Required for excision 1-B domain-containing protein

1

0

High-throughput

0.265

Low

1342733

MUCEN
Endomucin

1

0

Small-scale

0.261

Low

352267

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

1165974

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

484484

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024