HitPredict

Interactor 1: MYO1B (O43795)
Unconventional myosin-Ib (MYH-1c) (Myosin I alpha) (MMI-alpha) (MMIa)
Gene: MYO1B

Interactor 2: INSRR (P14616)
Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]
Gene: INSRR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1136 Hs			1 1297
+	Hs
		297285 MYO1D_HUMAN (16-794): 0: 706: 47.73		INSRR_HUMAN (1-1297): 0: 1365: 100.00
+	Hs
		214540 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		EPHA4_HUMAN (455-1279): 0: 609: 20.55
+	Hs
		214583 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		EPHA7_HUMAN (454-1280): 0: 598: 20.58
+	Hs
		214511 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		EPHA2_HUMAN (455-1282): 9.77e-179: 556: 21.20
+	Hs
		214500 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		EPHA1_HUMAN (657-1279): 2.19e-159: 505: 23.51
+	Hs
		214465 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91
+	Hs
		214588 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		NTRK3_HUMAN (957-1242): 2.05e-62: 231: 40.84
+	Hs
		297426 MYO1D_HUMAN (16-794): 0: 706: 47.73		EPHA6_HUMAN (454-1254): 0: 578: 19.82
+	Hs
		297302 MYO1D_HUMAN (16-794): 0: 706: 47.73		EPHA2_HUMAN (455-1282): 9.77e-179: 556: 21.20
+	Hs
		385783 MYO5A_HUMAN (2-1125): 0: 1013: 28.64		NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91
+	Hs
		297294 MYO1D_HUMAN (16-794): 0: 706: 47.73		EPHA1_HUMAN (657-1279): 2.19e-159: 505: 23.51
+	Hs
		117602 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		EPHA2_HUMAN (455-1282): 9.77e-179: 556: 21.20
+	Hs
		117721 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		EPHAA_HUMAN (657-1253): 2.9e-139: 452: 23.91
+	Hs
		665375 MYH9_HUMAN (694-1133): 5.37e-12: 72.7: 7.63		EPHA3_HUMAN (453-1255): 0: 617: 21.02
+	Hs
		117552 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91
+	Hs
		725069 MYH9_HUMAN (694-1133): 5.37e-12: 72.7: 7.63		ALK_HUMAN (946-1247): 1.07e-70: 263: 43.46
+	Hs
		725268 MYH10_HUMAN (771-1132): 7.68e-10: 65.8: 7.47		ALK_HUMAN (946-1247): 1.07e-70: 263: 43.46
+	Hs
		384384 MYH9_HUMAN (694-1133): 5.37e-12: 72.7: 7.63		NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91
+	Hs
		384385 MYH10_HUMAN (771-1132): 7.68e-10: 65.8: 7.47		NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91