HitPredict

Interactor 1: SAHH2 (O43865)
S-adenosylhomocysteine hydrolase-like protein 1 (DC-expressed AHCY-like molecule) (IP(3)Rs binding protein released with IP(3)) (IRBIT) (Putative adenosylhomocysteinase 2) (S-adenosyl-L-homocysteine hydrolase 2) (AdoHcyase 2)
Gene: AHCYL1

Interactor 2: PI42B (P78356)
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (PtdIns(5)P-4-kinase isoform 2-beta)
Gene: PIP4K2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 416
+	Hs
		942436 SAHH3_HUMAN (7-530): 0: 879: 86.43		PI42B_HUMAN (1-416): 0: 513: 100.00
+	Hs
		216556 SAHH2_HUMAN (1-530): 0: 909: 100.00		PI42C_HUMAN (2-415): 4.34e-169: 481: 64.05
+	Hs
		216467 SAHH2_HUMAN (1-530): 0: 909: 100.00		PI42A_HUMAN (14-416): 5.22e-164: 468: 77.92
+	Hs
		1253112 SAHH3_HUMAN (7-530): 0: 879: 86.43		PI42C_HUMAN (2-415): 4.34e-169: 481: 64.05
+	Hs
		817727 SAHH3_HUMAN (7-530): 0: 879: 86.43		PI42A_HUMAN (14-416): 5.22e-164: 468: 77.92
+	Hs
		1293637 SAHH3_HUMAN (7-530): 0: 879: 86.43		PI51A_HUMAN (10-415): 1.41e-159: 463: 30.64