HitPredict

Interactor 1: AIRE (O43918)
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein)
Gene: AIRE

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.804

The method score is based on:

Property Details
Experiments 10748110, 12929931
Identification Methods two hybrid, far western blotting
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Bromodomain~PHD
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006355 - regulation of DNA-templated transcription
GO:0008270 - zinc ion binding
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024