Protein: FARP2
FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain-including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) (Pleckstrin homology domain-containing family C member 3) (PH domain-containing family C member 3)

Gene: FARP2
Organism: Homo sapiens
Interactions: 87
UniProt ID: O94887

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0007155 - cell adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

320547

PLK1
Serine/threonine-protein kinase PLK1

3

6

High-throughput

0.847

High

320542

KPCI
Protein kinase C iota type

2

9

High-throughput

0.811

High

320545

KC1E
Casein kinase I isoform epsilon

2

4

High-throughput

0.811

High

320531

VAV
Proto-oncogene vav

2

11

High-throughput

0.737

High

320532

CHIN
N-chimaerin

2

11

High-throughput

0.737

High

320555

KPCZ
Protein kinase C zeta type

2

9

High-throughput

0.737

High

320528

CDK4
Cyclin-dependent kinase 4

1

4

Small-scale

0.724

High

320553

CDK6
Cyclin-dependent kinase 6

1

4

Small-scale

0.724

High

320588

PSD2
PH and SEC7 domain-containing protein 2

1

5

High-throughput

0.691

High

320548

ICLN
Methylosome subunit pICln

3

6

High-throughput

0.675

High

162413

ANM5
Protein arginine N-methyltransferase 5

2

2

High-throughput

0.628

High

320520

HERC2
E3 ubiquitin-protein ligase HERC2

2

6

High-throughput

0.628

High

320552

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

2

4

High-throughput

0.628

High

320560

GRDN
Girdin

2

13

High-throughput

0.628

High

320578

TRI41
E3 ubiquitin-protein ligase TRIM41

2

3

High-throughput

0.628

High

320589

RIOK1
Serine/threonine-protein kinase RIO1

2

2

High-throughput

0.628

High

320521

RASN
GTPase NRas

1

20

High-throughput

0.618

High

320522

RASK
GTPase KRas

1

20

High-throughput

0.618

High

320526

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.618

High

320536

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

320566

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.618

High

320585

Q96D37
VAV1 protein

1

10

High-throughput

0.618

High

320558

RNPS1
RNA-binding protein with serine-rich domain 1

2

9

High-throughput

0.601

High

320599

KCNE3
Potassium voltage-gated channel subfamily E member 3

2

1

High-throughput

0.601

High

320549

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

19

High-throughput

0.575

High

230608

PRIC3
Prickle planar cell polarity protein 3

2

10

High-throughput

0.574

High

320533

ACM3
Muscarinic acetylcholine receptor M3

2

2

High-throughput

0.574

High

320567

MISP
Mitotic interactor and substrate of PLK1

2

5

High-throughput

0.574

High

320574

GP156
Probable G-protein coupled receptor 156

2

2

High-throughput

0.574

High

320523

ESR1
Estrogen receptor

2

17

High-throughput

0.571

High

320535

DNJB1
DnaJ homolog subfamily B member 1

2

1

High-throughput

0.571

High

320598

NOC2L
Nucleolar complex protein 2 homolog

2

1

High-throughput

0.571

High

320591

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

19

High-throughput

0.553

High

320540

RS19
Small ribosomal subunit protein eS19

1

3

High-throughput

0.536

High

320544

SRP09
Signal recognition particle 9 kDa protein

1

2

High-throughput

0.536

High

320569

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

320570

KIBRA
Protein KIBRA

1

11

High-throughput

0.536

High

320575

ARRD2
Arrestin domain-containing protein 2

1

7

High-throughput

0.536

High

320579

PSPC1
Paraspeckle component 1

1

2

High-throughput

0.536

High

320583

ARRD3
Arrestin domain-containing protein 3

1

7

High-throughput

0.536

High

320593

COPRS
Coordinator of PRMT5 and differentiation stimulator

1

1

High-throughput

0.536

High

320550

UB2G2
Ubiquitin-conjugating enzyme E2 G2

1

0

High-throughput

0.518

High

320534

FGFR3
Fibroblast growth factor receptor 3

1

20

High-throughput

0.514

High

320561

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.513

High

320527

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

6

High-throughput

0.501

High

320530

CADH1
Cadherin-1

1

12

Small-scale

0.501

High

74417

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

2

High-throughput

0.489

High

191499

MAGB2
Melanoma-associated antigen B2

1

5

High-throughput

0.489

High

320538

CD6
T-cell differentiation antigen CD6

1

8

High-throughput

0.489

High

320594

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

2

High-throughput

0.489

High

320564

NHRF3
Na(+)/H(+) exchange regulatory cofactor NHE-RF3

1

14

Small-scale

0.481

High

172349

XPO1
Exportin-1

1

3

High-throughput

0.479

High

211245

RFOX2
RNA binding protein fox-1 homolog 2

1

3

High-throughput

0.479

High

240340

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

320524

TBB4A
Tubulin beta-4A chain

1

4

High-throughput

0.479

High

320525

P53
Cellular tumor antigen p53

1

7

High-throughput

0.479

High

320539

STIP1
Stress-induced-phosphoprotein 1

1

4

High-throughput

0.479

High

320541

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

320554

TF65
Transcription factor p65

1

7

High-throughput

0.479

High

320557

CUL3
Cullin-3

1

3

High-throughput

0.479

High

320563

AGK
Acylglycerol kinase, mitochondrial

1

1

High-throughput

0.479

High

320565

CBPC6
Cytosolic carboxypeptidase 6

1

1

Small-scale

0.479

High

320581

KAT6A
Histone acetyltransferase KAT6A

1

5

High-throughput

0.479

High

320592

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

320595

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

320596

XPO7
Exportin-7

1

3

High-throughput

0.479

High

320597

PRP19
Pre-mRNA-processing factor 19

1

4

High-throughput

0.479

High

320571

NUP93
Nuclear pore complex protein Nup93

1

0

High-throughput

0.458

High

320587

MYCBP
c-Myc-binding protein

1

0

High-throughput

0.458

High

320562

KLH22
Kelch-like protein 22

1

5

High-throughput

0.445

High

320551

MAX
Protein max

1

6

High-throughput

0.437

High

320568

MGAP
MAX gene-associated protein

1

1

High-throughput

0.437

High

320577

TM263
Transmembrane protein 263

1

1

High-throughput

0.437

High

320580

ESR2
Estrogen receptor beta

1

16

High-throughput

0.437

High

320582

CK052
Uncharacterized protein C11orf52

1

7

High-throughput

0.437

High

320590

NSRP1
Nuclear speckle splicing regulatory protein 1

1

4

High-throughput

0.437

High

320572

LAT4
Large neutral amino acids transporter small subunit 4

1

5

High-throughput

0.407

High

320576

ZCH10
Zinc finger CCHC domain-containing protein 10

1

7

High-throughput

0.407

High

320543

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

0

High-throughput

0.347

High

320529

PIP
Prolactin-inducible protein

2

0

High-throughput

0.313

High

320546

SSRD
Translocon-associated protein subunit delta

2

0

High-throughput

0.298

High

320573

PNKD
Probable thioesterase PNKD

2

0

High-throughput

0.298

High

320537

NK3R
Neuromedin-K receptor

1

0

High-throughput

0.279

Low

320556

NOGG
Noggin

1

0

High-throughput

0.279

Low

320559

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

320586

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.279

Low

320584

CC049
Putative uncharacterized protein C3orf49

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025