HitPredict

Interactor 1: PDE6D (O43924)
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (GMP-PDE delta) (Protein p17)
Gene: PDE6D

Interactor 2: RAP1A (P62834)
Ras-related protein Rap-1A (EC 3.6.5.2) (C21KG) (G-22K) (GTP-binding protein smg p21A) (Ras-related protein Krev-1)
Gene: RAP1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.645

Property	Details
Experiments	11786539, 11980706, 30257685
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031267 - small GTPase binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 150 Hs			1 184
+	Hs
		217716 PDE6D_HUMAN (1-150): 1.96e-98: 281: 100.00		RAP2B_HUMAN (1-166): 9.28e-65: 198: 66.27
+	Hs
		217694 PDE6D_HUMAN (1-150): 1.96e-98: 281: 100.00		RASK_HUMAN (1-184): 8.24e-56: 176: 54.45
+	Hs
		217693 PDE6D_HUMAN (1-150): 1.96e-98: 281: 100.00		RASH_HUMAN (1-180): 7.38e-55: 173: 55.00