HitPredict

Interactor 1: DDB1B (O49552)
DNA damage-binding protein 1b (UV-damaged DNA-binding protein 1b) (DDB1b)
Gene: DDB1B

Interactor 2: THOC6 (Q8L4M1)
THO complex subunit 6 (AtTHO6) (Protein DWD HYPERSENSITIVE TO ABA 1) (WD repeat-containing protein DWA1)
Gene: THO6

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	18223036, 20525848
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CPSF_A~WD40, MMS1_N~WD40
Common GO terms	GO:0005634 - nucleus GO:0016567 - protein ubiquitination
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1088 At			1 367
+	At
		1225938 DDB1A_ARATH (1-1088): 0: 1312: 91.27		THOC6_ARATH (1-367): 2.48e-86: 267: 93.65
+	At
		221824 DDB1B_ARATH (1-1088): 0: 1316: 100.00		PRL1_ARATH (146-348): 3.89e-23: 102: 17.84
+	At
		1114755 DDB1A_ARATH (1-1088): 0: 1312: 91.27		PRL1_ARATH (146-348): 3.89e-23: 102: 17.84
+	Hs
		1082374 DDB1_HUMAN (3-1088): 0: 1202: 51.13		TBL1R_HUMAN (141-365): 2.56e-44: 161: 12.12
+	Hs
		245605 DDB1_HUMAN (3-1088): 0: 1202: 51.13		TBL1X_HUMAN (131-361): 9.73e-44: 160: 13.53
+	Hs
		1082206 DDB1_HUMAN (3-1088): 0: 1202: 51.13		SMU1_HUMAN (187-366): 6.14e-38: 144: 19.80
+	Hs
		903254 DDB1_HUMAN (3-1088): 0: 1202: 51.13		WDR5_HUMAN (234-366): 3.29e-33: 127: 17.86
+	Hs
		1082263 DDB1_HUMAN (3-1088): 0: 1202: 51.13		WDR5B_HUMAN (2-186): 2.33e-19: 89.4: 11.11
+	Hs
		1073168 SF3B3_HUMAN (3-1085): 0: 1013: 21.29		NLE1_HUMAN (2-273): 2.67e-50: 176: 13.74
+	Hs
		1073094 SF3B3_HUMAN (3-1085): 0: 1013: 21.29		FBXW7_HUMAN (4-266): 1.29e-47: 173: 14.53
+	Hs
		267761 SF3B3_HUMAN (3-1085): 0: 1013: 21.29		TAF5L_HUMAN (4-219): 1.07e-34: 135: 14.10
+	Sc
		744701 CFT1_YEAST (12-1072): 0: 618: 15.33		TAF5_YEAST (148-366): 3.93e-55: 194: 15.98
+	Sc
		980241 RSE1_YEAST (3-1085): 0: 646: 16.56		PRP46_YEAST (38-354): 3.94e-37: 141: 16.92
+	Hs
		1014208 CPSF1_HUMAN (3-519): 7.47e-118: 398: 17.30		NLE1_HUMAN (2-273): 2.67e-50: 176: 13.74
+	Hs
		197009 CPSF1_HUMAN (3-519): 7.47e-118: 398: 17.30		PRP4_HUMAN (2-228): 1.15e-42: 157: 12.30
+	Hs
		1014128 CPSF1_HUMAN (3-519): 7.47e-118: 398: 17.30		TAF5_HUMAN (2-188): 2.66e-35: 138: 9.01