HitPredict

Interactor 1: DDB1B (O49552)
DNA damage-binding protein 1b (UV-damaged DNA-binding protein 1b) (DDB1b)
Gene: DDB1B

Interactor 2: CUL4 (Q8LGH4)
Cullin-4 (AtCUL4)
Gene: CUL4

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	1.00	0.878

Property	Details
Experiments	16792691, 18223036, 20061554, 24067658
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	CPSF_A~Cullin, Cullin~MMS1_N
Common GO terms	GO:0005634 - nucleus GO:0006281 - DNA repair
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1088 At			1 792
+	At
		1228145 DDB1A_ARATH (1-1088): 0: 1312: 91.27		CUL4_ARATH (1-792): 0: 944: 100.00
+	Hs
		1043374 DDB1_HUMAN (3-1088): 0: 1202: 51.13		CUL4B_HUMAN (29-792): 0: 925: 55.95
+	Mm
		1111812 DDB1_MOUSE (3-1088): 0: 1204: 51.22		CUL4A_MOUSE (34-792): 0: 923: 55.26
+	Mm
		56795 DDB1_MOUSE (3-1088): 0: 1204: 51.22		CUL4B_MOUSE (25-792): 0: 917: 55.40
+	Hs
		1043013 DDB1_HUMAN (3-1088): 0: 1202: 51.13		CUL4A_HUMAN (34-792): 0: 915: 55.79
+	Hs
		1041668 DDB1_HUMAN (3-1088): 0: 1202: 51.13		CUL3_HUMAN (60-792): 0: 834: 38.63
+	Dm
		1124382 DDB1_DROME (3-1088): 0: 1098: 45.16		Q5BI50_DROME (8-792): 0: 926: 52.90
+	Hs
		1041008 DDB1_HUMAN (3-1088): 0: 1202: 51.13		CUL1_HUMAN (93-792): 0: 758: 29.37
+	Hs
		1043002 SF3B3_HUMAN (3-1085): 0: 1013: 21.29		CUL4A_HUMAN (34-792): 0: 915: 55.79
+	Hs
		1041634 SF3B3_HUMAN (3-1085): 0: 1013: 21.29		CUL3_HUMAN (60-792): 0: 834: 38.63
+	Hs
		1082313 DDB1_HUMAN (3-1088): 0: 1202: 51.13		CUL5_HUMAN (92-792): 0: 610: 25.68
+	Hs
		1040995 SF3B3_HUMAN (3-1085): 0: 1013: 21.29		CUL1_HUMAN (93-792): 0: 758: 29.37
+	Hs
		1041332 SF3B3_HUMAN (3-1085): 0: 1013: 21.29		CUL2_HUMAN (91-792): 0: 717: 26.44
+	Ce
		1088892 DDB1_CAEEL (5-1088): 0: 931: 33.33		CUL4_CAEEL (6-792): 0: 664: 30.63
+	Sp
		143266 DDB1_SCHPO (6-1088): 0: 809: 26.25		CUL4_SCHPO (69-788): 0: 652: 32.16
+	Hs
		1014118 CPSF1_HUMAN (3-519): 7.47e-118: 398: 17.30		CUL4A_HUMAN (34-792): 0: 915: 55.79
+	Sp
		144468 RIK1_SCHPO (13-1088): 0: 650: 20.98		CUL4_SCHPO (69-788): 0: 652: 32.16
+	Hs
		1014117 CPSF1_HUMAN (3-519): 7.47e-118: 398: 17.30		CUL3_HUMAN (60-792): 0: 834: 38.63