Interactor 1: EOMES (O54839)
Eomesodermin homolog (T-box brain protein 2) (T-brain-2) (TBR-2)
Gene: EOMES

Interactor 2: CDX2 (P43241)
Homeobox protein CDX-2 (Caudal-type homeobox protein 2)
Gene: CDX2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 26206133
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Homeodomain~T-box
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001824 - blastocyst development
and 9 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 707
Mm

1 311
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Ce
+ Ce
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024