HitPredict

Interactor 1: GLT (O59010)
Glutamate transporter homolog (Glt(Ph)) (Sodium-aspartate symporter Glt(Ph)) (Sodium-dependent aspartate transporter)
Gene: PH1295

Interactor 2: GLT (O59010)
Glutamate transporter homolog (Glt(Ph)) (Sodium-aspartate symporter Glt(Ph)) (Sodium-dependent aspartate transporter)
Gene: PH1295

Species: Pyrococcus horikoshii OT3

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 19924125, 22343718, 23334289, 23334291, 23563139, 23792560, 24091978, 25652997
Identification Methods x-ray crystallography, molecular sieving, electron paramagnetic resonance, fluorescent resonance energy transfer
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SDF~SDF
Common GO terms GO:0005283 - amino acid:sodium symporter activity
GO:0005886 - plasma membrane
GO:0015108 - chloride transmembrane transporter activity
GO:0015183 - L-aspartate transmembrane transporter activity
GO:0046872 - metal ion binding
and 4 others

more...
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 425
Ph

1 425
+ Hs
+ Mm
+ Tk
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024