HitPredict

Interactor 1: RUXF (O59734)
Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF)
Gene: smf1

Interactor 2: LSM3 (Q9Y7M4)
Probable U6 snRNA-associated Sm-like protein LSm3
Gene: LSM3

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	26771498
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005686 - U2 snRNP GO:0046540 - U4/U6 x U5 tri-snRNP complex and 1 others more... GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 78 Sp			1 93
+	Hs
		912139 LSM6_HUMAN (1-77): 3.99e-32: 108: 40.26		LSM3_HUMAN (2-91): 4.02e-32: 109: 57.78
+	Hs
		912211 LSM4_HUMAN (6-76): 3.2e-31: 107: 30.56		LSM3_HUMAN (2-91): 4.02e-32: 109: 57.78
+	Hs
		911791 RUXF_HUMAN (4-74): 2.86e-31: 106: 67.61		LSM3_HUMAN (2-91): 4.02e-32: 109: 57.78
+	Dm
		1213197 Q9VKW8_DROME (6-76): 3.43e-31: 108: 30.56		Q8IMX8_DROME (7-91): 4.5e-31: 106: 63.53
+	Hs
		912220 LSM6_HUMAN (1-77): 3.99e-32: 108: 40.26		RSMN_HUMAN (16-93): 1.55e-24: 93.8: 19.51
+	Hs
		928049 LSM4_HUMAN (6-76): 3.2e-31: 107: 30.56		RSMN_HUMAN (16-93): 1.55e-24: 93.8: 19.51
+	Hs
		538893 LSM6_HUMAN (1-77): 3.99e-32: 108: 40.26		RSMB_HUMAN (16-93): 5.17e-24: 92.6: 20.73
+	Hs
		912256 LSM6_HUMAN (1-77): 3.99e-32: 108: 40.26		LSM7_HUMAN (2-90): 1.53e-25: 92.6: 29.21
+	Hs
		1356296 LSM4_HUMAN (6-76): 3.2e-31: 107: 30.56		LSM7_HUMAN (2-90): 1.53e-25: 92.6: 29.21
+	Hs
		539204 LSM4_HUMAN (6-76): 3.2e-31: 107: 30.56		RSMB_HUMAN (16-93): 5.17e-24: 92.6: 20.73
+	Hs
		538890 RUXF_HUMAN (4-74): 2.86e-31: 106: 67.61		RSMB_HUMAN (16-93): 5.17e-24: 92.6: 20.73
+	Dm
		1368675 Q9VKW8_DROME (6-76): 3.43e-31: 108: 30.56		Q9VJI7_DROME (2-90): 3.29e-24: 89.6: 26.97
+	Dm
		1367655 Q9VKW8_DROME (6-76): 3.43e-31: 108: 30.56		SMD2_DROME (6-88): 2.8e-23: 87.6: 30.23
+	Hs
		912259 LSM6_HUMAN (1-77): 3.99e-32: 108: 40.26		LSM5_HUMAN (10-84): 7.94e-23: 85.7: 25.33
+	Hs
		1377916 LSM4_HUMAN (6-76): 3.2e-31: 107: 30.56		LSM5_HUMAN (10-84): 7.94e-23: 85.7: 25.33
+	Dm
		1369695 Q9VKW8_DROME (6-76): 3.43e-31: 108: 30.56		Q9VRT7_DROME (10-83): 2.95e-22: 84.2: 25.68
+	Hs
		912218 LSM6_HUMAN (1-77): 3.99e-32: 108: 40.26		SMD2_HUMAN (6-88): 6.66e-22: 84.2: 29.07
+	Hs
		912602 LSM4_HUMAN (6-76): 3.2e-31: 107: 30.56		SMD2_HUMAN (6-88): 6.66e-22: 84.2: 29.07
+	Hs
		912021 LSM6_HUMAN (1-77): 3.99e-32: 108: 40.26		RUXG_HUMAN (7-88): 5.38e-18: 73: 24.39
+	Hs
		911790 RUXF_HUMAN (4-74): 2.86e-31: 106: 67.61		RUXG_HUMAN (7-88): 5.38e-18: 73: 24.39