Interactor 1: RAD21 (O60216)
Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog) [Cleaved into: 64-kDa C-terminal product (64-kDa carboxy-terminal product) (65-kDa carboxy-terminal product)]
Gene: RAD21

Interactor 2: REC8 (O95072)
Meiotic recombination protein REC8 homolog (Cohesin Rec8p)
Gene: REC8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Rad21_Rec8~Rad21_Rec8_N
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0006302 - double-strand break repair
GO:0007062 - sister chromatid cohesion
GO:0007131 - reciprocal meiotic recombination
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 631
Hs

1 547
+ Mm

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Last updated: 15 Jul 2024