HitPredict

Interactor 1: MED14 (O60244)
Mediator of RNA polymerase II transcription subunit 14 (Activator-recruited cofactor 150 kDa component) (ARC150) (Cofactor required for Sp1 transcriptional activation subunit 2) (CRSP complex subunit 2) (Mediator complex subunit 14) (RGR1 homolog) (hRGR1) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150)
Gene: MED14

Interactor 2: CTDP1 (Q9Y5B0)
RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase)
Gene: CTDP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	35271311, 16239144
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1454 Hs			1 961
+	Hs
		625111 RPB1_HUMAN (1059-1159): 8.88e-09: 62.5: 23.30		CTDP1_HUMAN (1-961): 0: 1152: 100.00
+	Hs
		149968 RPB1_HUMAN (1059-1159): 8.88e-09: 62.5: 23.30		CTDS2_HUMAN (89-347): 8.56e-72: 240: 17.29
+	Hs
		625028 RPB1_HUMAN (1059-1159): 8.88e-09: 62.5: 23.30		CTDS1_HUMAN (123-347): 7.8e-65: 220: 18.86