Interactor 1: AAKB2 (O43741)
5'-AMP-activated protein kinase subunit beta-2 (AMPK subunit beta-2)
Gene: PRKAB2

Interactor 2: AAKG1 (P54619)
5'-AMP-activated protein kinase subunit gamma-1 (AMPK gamma1) (AMPK subunit gamma-1) (AMPKg)
Gene: PRKAG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.985

The method score is based on:

Property Details
Experiments 26186194, 28514442, 31900314, 33961781, 10698692, 20562859, 25416956, 32296183, 32707033, 19616115, 21988832, 24722188, unassigned1304, unassigned3799
Identification Methods affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AMPK1_CBM~CBS, AMPKBI~CBS
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006633 - fatty acid biosynthetic process
and 4 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 272
Hs

1 331
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Rn
+ Hs
+ Dm
+ Sp
+ At
+ At
+ Sc
+ Sc
+ Zm
+ At
+ At
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 11Aug2025