HitPredict

Interactor 1: FGF17 (O60258)
Fibroblast growth factor 17 (FGF-17)
Gene: FGF17

Interactor 2: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	1.00	0.527

Property	Details
Experiments	18199118
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	FGF~I-set
Common GO terms	GO:0005576 - extracellular region GO:0008284 - positive regulation of cell population proliferation GO:0008543 - fibroblast growth factor receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 216 Hs			1 822
+	Hs
		507927 FGF8_HUMAN (28-214): 5.33e-64: 199: 62.50		FGFR1_HUMAN (1-822): 0: 861: 100.00
+	Hs
		181657 FGF10_HUMAN (21-178): 3.12e-61: 191: 22.67		FGFR1_HUMAN (1-822): 0: 861: 100.00
+	Hs
		225918 FGF17_HUMAN (1-216): 9.12e-80: 239: 100.00		FGFR2_HUMAN (1-821): 0: 803: 71.21
+	Hs
		507874 FGF9_HUMAN (49-181): 1.06e-55: 177: 28.57		FGFR1_HUMAN (1-822): 0: 861: 100.00
+	Mm
		555263 FGF9_MOUSE (49-181): 1.22e-55: 177: 28.57		FGFR1_MOUSE (1-822): 0: 860: 98.42
+	Hs
		441802 FGF4_HUMAN (40-178): 2.48e-51: 166: 29.79		FGFR1_HUMAN (1-822): 0: 861: 100.00
+	Mm
		555273 FGF21_MOUSE (26-215): 7.92e-52: 167: 16.92		FGFR1_MOUSE (1-822): 0: 860: 98.42
+	Hs
		499375 FGF6_HUMAN (50-178): 1.82e-50: 164: 31.30		FGFR1_HUMAN (1-822): 0: 861: 100.00
+	Hs
		601112 FGF7_HUMAN (6-177): 2.82e-73: 221: 27.57		FGFR2_HUMAN (1-821): 0: 803: 71.21
+	Hs
		601485 FGF8_HUMAN (28-214): 5.33e-64: 199: 62.50		FGFR2_HUMAN (1-821): 0: 803: 71.21
+	Hs
		181659 FGF10_HUMAN (21-178): 3.12e-61: 191: 22.67		FGFR2_HUMAN (1-821): 0: 803: 71.21
+	Hs
		601468 FGF9_HUMAN (49-181): 1.06e-55: 177: 28.57		FGFR2_HUMAN (1-821): 0: 803: 71.21
+	Hs
		441808 FGF4_HUMAN (40-178): 2.48e-51: 166: 29.79		FGFR2_HUMAN (1-821): 0: 803: 71.21
+	Hs
		601113 FGF7_HUMAN (6-177): 2.82e-73: 221: 27.57		FGFR3_HUMAN (6-821): 0: 730: 61.22
+	Mm
		740709 FGF8_MOUSE (27-214): 9.73e-63: 198: 61.86		FGFR3_MOUSE (1-799): 0: 740: 61.71
+	Hs
		609227 FGF8_HUMAN (28-214): 5.33e-64: 199: 62.50		FGFR3_HUMAN (6-821): 0: 730: 61.22
+	Mm
		867550 FGF9_MOUSE (49-181): 1.22e-55: 177: 28.57		FGFR3_MOUSE (1-799): 0: 740: 61.71
+	Hs
		609185 FGF9_HUMAN (49-181): 1.06e-55: 177: 28.57		FGFR3_HUMAN (6-821): 0: 730: 61.22
+	Hs
		441809 FGF4_HUMAN (40-178): 2.48e-51: 166: 29.79		FGFR3_HUMAN (6-821): 0: 730: 61.22
+	Mm
		975161 FGF21_MOUSE (26-215): 7.92e-52: 167: 16.92		FGFR4_MOUSE (4-806): 0: 676: 54.70