HitPredict

Interactor 1: KLK8 (O60259)
Kallikrein-8 (hK8) (EC 3.4.21.118) (Neuropsin) (NP) (Ovasin) (Serine protease 19) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein)
Gene: KLK8

Interactor 2: RB39B (Q96DA2)
Ras-related protein Rab-39B
Gene: RAB39B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0050808 - synapse organization
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 260 Hs			1 213
+	Hs
		225964 KLK8_HUMAN (1-260): 8.28e-126: 359: 100.00		RB39A_HUMAN (1-213): 1.89e-81: 243: 76.96
+	Hs
		1328149 TMPS4_HUMAN (6-259): 1.55e-93: 283: 31.46		RAB1B_HUMAN (1-213): 1.12e-85: 253: 38.50
+	Mm
		371651 CFAD_MOUSE (15-255): 5.96e-45: 153: 38.65		RAB2A_MOUSE (5-213): 3.41e-94: 275: 43.87
+	Mm
		371729 CFAD_MOUSE (15-255): 5.96e-45: 153: 38.65		RAB1A_MOUSE (1-213): 1.02e-85: 253: 39.44
+	Mm
		372506 CFAD_MOUSE (15-255): 5.96e-45: 153: 38.65		RAB1B_MOUSE (1-213): 1.82e-85: 253: 38.50
+	Mm
		371618 CFAD_MOUSE (15-255): 5.96e-45: 153: 38.65		RB11B_MOUSE (2-213): 3.05e-81: 242: 39.44
+	Mm
		372283 CFAD_MOUSE (15-255): 5.96e-45: 153: 38.65		RAB14_MOUSE (4-213): 9.62e-81: 241: 38.86
+	Mm
		371657 CFAD_MOUSE (15-255): 5.96e-45: 153: 38.65		RAB8A_MOUSE (1-171): 3.61e-55: 176: 49.71