HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: K2C7 (P08729)
Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin) (Type-II keratin Kb7)
Gene: KRT7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 469
+	Hs
		226262 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		K2C8_HUMAN (1-439): 3.58e-162: 468: 61.28
+	Hs
		227198 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		K22O_HUMAN (63-419): 1.75e-159: 467: 66.48
+	Hs
		312447 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		K2C8_HUMAN (1-439): 3.58e-162: 468: 61.28
+	Hs
		226160 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		K2C75_HUMAN (3-468): 1.11e-85: 275: 57.32
+	Hs
		227741 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		K2C79_HUMAN (7-415): 1.74e-84: 271: 58.17
+	Hs
		226231 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		K2C6B_HUMAN (56-462): 1.1e-74: 246: 64.95
+	Hs
		226397 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		K2C5_HUMAN (56-413): 6.78e-73: 242: 71.87
+	Hs
		312606 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		K2C72_HUMAN (7-468): 4.16e-79: 256: 54.00
+	Hs
		475775 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		K2C72_HUMAN (7-468): 4.16e-79: 256: 54.00