HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: CSTF2 (P33240)
Cleavage stimulation factor subunit 2 (CF-1 64 kDa subunit) (Cleavage stimulation factor 64 kDa subunit) (CSTF 64 kDa subunit) (CstF-64)
Gene: CSTF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35987950
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 577
+	Hs
		228645 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CSTFT_HUMAN (1-576): 3.87e-55: 198: 67.64
+	Hs
		227414 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CIRBP_HUMAN (17-94): 4.28e-34: 129: 34.62
+	Hs
		227354 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP4_HUMAN (7-299): 7.22e-25: 111: 16.67
+	Hs
		226375 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP1_HUMAN (6-193): 8.03e-24: 107: 16.32
+	Hs
		227642 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PAP1L_HUMAN (7-268): 2.63e-23: 106: 13.16
+	Hs
		228678 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP3_HUMAN (6-206): 2.79e-23: 106: 15.27
+	Hs
		1031383 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		PABP4_HUMAN (7-299): 7.22e-25: 111: 16.67
+	Hs
		312602 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		CIRBP_HUMAN (17-94): 4.28e-34: 129: 34.62
+	Hs
		312462 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		PABP1_HUMAN (6-193): 8.03e-24: 107: 16.32
+	Hs
		475739 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		CIRBP_HUMAN (17-94): 4.28e-34: 129: 34.62
+	Hs
		475631 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		RBM3_HUMAN (17-94): 4.1e-33: 126: 39.74
+	At
		975638 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		RBG8_ARATH (19-93): 1.75e-33: 127: 33.33
+	Hs
		475708 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP4_HUMAN (7-299): 7.22e-25: 111: 16.67
+	Hs
		475288 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP1_HUMAN (6-193): 8.03e-24: 107: 16.32
+	At
		981214 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		CP31A_ARATH (17-147): 1.24e-22: 101: 24.44
+	At
		186465 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PABP4_ARATH (16-190): 1.21e-20: 98.2: 19.66
+	At
		983451 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PABP5_ARATH (11-199): 1.01e-18: 92: 18.23